West Ham's 3-0 defeat at Brentford offered Tottenham a lifeline in the battle for Premier League survival on Saturday.
Spurs remain in the relegation zone, two points from safety, but can move out of the bottom three with victory at Aston Villa on Sunday after the Hammers succumbed to just their third defeat in 11 league games.
Brentford boosted their chances of European qualification for the first time with a first win in eight matches.
Konstantinos Mavropanos was left to rue his luck in two key first-half incidents.
The Greek defender was unfortunate not to be awarded a free-kick as he turned the ball into his own net to open the scoring.
Mavropanos thought he had made amends moments later with a bullet header, but was ruled marginally offside by a VAR review.
Brentford had another call go in their favour early in the second half when Dango Ouattara won a penalty and Igor Thiago coolly converted his 22nd Premier League goal of the season.
Mikkel Damsgaard's strike rounded off a damaging day for West Ham, who face title-chasing Arsenal next weekend.
Brentford move up to sixth, which could be enough to secure Champions League qualification.
